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Selective GLP-1 Agonist Once-Weekly FlexTouch NICE TA875 Approved

Wegovy (Semaglutide): The Gold Standard Weekly Weight Loss Pen

Wegovy is Novo Nordisk's clinically approved weekly semaglutide injection specifically engineered for chronic weight management. Proven in rigorous clinical trials to reduce body weight by an average of ~15%.

~15.0%
Avg Weight Loss
Weekly
Dosing Interval
0.25 - 2.4mg
Dosing Range

Key Prescription Facts

Active Ingredient:
Semaglutide
Manufacturer:
Novo Nordisk
Device:
FlexTouch Pen (4 Doses)
Administration:
Subcutaneous (Once Weekly)
Eligibility:
BMI ≥ 30 (or ≥ 27 w/ risk)
Dispensed by:
Click Pharmacy (UK)

How Does Wegovy Work for Weight Loss?

Wegovy mimics the actions of human glucagon-like peptide-1 (GLP-1), a physiological hormone that regulates appetite and caloric intake. Semaglutide works via three principal clinical pathways:

1. Appetite Reduction

Directly targets appetite control receptors in the hypothalamus, decreasing feelings of hunger and subduing cravings.

2. Slower Digestion

Slows gastric emptying rate, helping meals remain in the stomach longer and extending sensations of satiety after smaller portions.

3. Blood Sugar Balance

Promotes glucose-dependent insulin secretion, preventing steep postprandial glucose spikes and energy crashes.

STEP-1 Clinical Trial: Clinically Proven Results

The landmark STEP-1 (Semaglutide Treatment Effect in People with Obesity) trial studied 1,961 adults over 68 weeks. The findings confirmed robust, sustained body weight reduction:

86.4%

Lost ≥ 5% of Body Weight

69.1%

Lost ≥ 10% of Body Weight

50.5%

Lost ≥ 15% of Body Weight

Reference: Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med 2021; 384:989-1002.

Wegovy 5-Step Dosing & Titration Schedule

Wegovy pens are color-coded by dose strength. You must spend a minimum of 4 weeks on each dose before stepping up:

0.25mg

Month 1 (Weeks 1 - 4): Initiation Dose

Pre-filled green pen. Initiates GLP-1 receptor adaptation without overloading the gastrointestinal tract.

0.50mg

Month 2 (Weeks 5 - 8): Second Step

Pre-filled pink pen. Appetite suppression becomes more noticeable.

1.00mg

Month 3 (Weeks 9 - 12): Intermediate Step

Pre-filled brown pen. Substantial caloric intake reduction and accelerated weight loss.

1.70mg

Month 4 (Weeks 13 - 16): Pre-Maintenance Dose

Pre-filled blue pen. Prepares patient for final maximum therapeutic dose.

2.40mg

Month 5+ (Week 17 Onward): Full Maintenance Dose

Pre-filled black/grey pen. The clinically proven maintenance dose for long-term weight management.

Fast UK Delivery

Consult with Click Pharmacy for Wegovy

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